Who does sickle cell affect?

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Over 3 to 4 million Americans carry the sickle cell trait, and there is a 25 percent chance that a child could inherit the disease when both parents are carriers. Roughly one in 500 African-Americans are born with the disease, and according to the Sickle Cell Disease Association of America and the CDC, typical sickle cell anemia sufferers live only until their mid-40s and some children sometimes wouldn’t live until the age of 5. Sickle cell anemia also seriously affects people whose ancestors come from South America, Central America, Cuba, Saudi Arabia, India, and Mediterranean countries such as Turkey, Greece and Italy.